ピコスルファートナトリウムあるいはセンノシドが原因と思われた固定薬疹

・臀部に生じた固定薬疹を経験した． ・原因薬剤の検索で，ピコスルファートナトリウム，センノシドの両剤で薬剤リンパ球刺激試験（DLST）陽性となった． ・両薬剤を中止し，ステロイド外用を開始したところ，皮疹は改善した． （「症例のポイント」より）

A case of fixed drug eruption caused by sodium picosulfate or sennoside

Michishita, Kazunori1）Ishida, Wataru2） 1）Department of Dermatology Toyama Red Cross Hospital 2）Department of Dermatology Tonami General Hospital

Abstract The patient was an 83-year-old man who was prescribed Sodium picosulfate and Sennoside for his constipation by a neighborhood doctor. He subsequently developed a rash a few months later. There was a black plaque on the hip, suggesting fixed drug eruption. The DLST(drug-induced lymphocyte stimulation test) was positive for both Sodium picosulfate and Sennoside, whereas patch test was negative. He was successfully treated with discontinuance of both medicines. We diagnosed this case as fixed drug eruption due to Sodium picosulfate or Sennoside．