Volume 26, Issue 10 (September 2016)
Japanese

Osteoporosis and Respiratory Diseases. Bone quality in COPD. Saito Mitsuru 1 , Marumo Keishi 2 1Department of Orthopaedic Surgery, Jikei University School of Medicine, Japan. 2Department of Orthopaedic Surgery, Jikei University School of Medicine, Japan. pp.1437-1444
Published Date 2016/9/28
DOI https://doi.org/10.20837/4201610059
  • Abstract
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 Chronic obstructive pulmonary disease(COPD)is a chronic inflammatory disease associated with an increase of fracture risk. Bone strength is determined by bone mass and quality.Bone quality is thought to encompass the structural and material properties of bone. Bone collagen crosslinking plays important roles in bone strength. The quantitative and qualitative deterioration of lysyl oxidase control and non enzymatic cross-links(advanced glycation end products, AGEs, pentosidine)of collagen in patients with osteoporotic femoral neck fracture and diabetes, and COPD might be affected by increased oxidative stress and glycation.



基本情報

09175857.26.10.jpg
CLINICAL CALCIUM
26巻10号 (2016年9月)
電子版ISSN 印刷版ISSN 0917-5857 医薬ジャーナル社

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