骨粗鬆症治療の全体像と治療目的

On"2015 Guidelines for Prevention and Treatment of Osteoporosis". Overview and the aim of the treatment of osteoporosis.

　骨粗鬆症の治療をする目的は骨折の抑制であり，骨粗鬆症治療は骨の健康維持を通じて骨格全体の健康維持に中心的な役割を果たす。骨粗鬆症の治療では食事療法や運動療法は基礎療法と位置付けられ，薬物療法が中心である。加齢にともなって有病率が高まる本疾患では治療開始基準が必要であり，骨粗鬆症の予防と治療ガイドラインでは診断基準とは別に骨折リスクによる薬物治療開始基準が定められているが，費用対効果に関しては十分なデータがないため加えられておらず，今後の課題である。

　The prevention of fragility fractures is related to the aim of the treatment of osteoporosis which plays a central role in maintaining skeletal health. Diet therapy and exercise are regarded as a very important part of base therapy while intervention along with pharmaceutical treatment are a large part of the main therapy. As the prevalence of osteoporosis increases with age, criteria for initiation of pharmacological treatment are essential. The basis for assessing fracture risk was established when the Japanese guidelines for prevention and treatment of osteoporosis was first implemented. However, cost-effectiveness analysis was not included since little data was available. This should be an issue for inclusion in considering treatment in the future.