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The usefulness of evaluating alteration of rCBF in disease specific areas of Alzheimer disease before and after medical therapy Risa Yokota 1 1Department of Radiology Faculty of Medicine, Fukuoka University Keyword: アルツハイマー型認知症 , 脳血流SPECT , 疾患特異領域 , 治療効果 pp.649-657
Published Date 2020/7/10
DOI https://doi.org/10.18888/rp.0000001288
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We investigated the usefulness of regional cerebral blood flow(rCBF)SPECT analysis in disease specific areas including precuneus and posterior cingulate in monitoring the therapeutic effect in patients with Alzheimer’s disease(AD). Twenty-four AD patients were divided into two groups according to the change of MMSE before and after therapy, namely the responder group and the non-responder group. The most patients who showed marked deterioration of disease specific areas of rCBF SPECT were in the non-responder group. The assessment of rCBF in disease specific areas will be useful objective method in monitoring AD patients.


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電子版ISSN 印刷版ISSN 0009-9252 金原出版

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