Journal of Japan Society of Nursing and Health Care Volume 16, Issue 2 (December 2014)
Japanese

Stress-Related Depression: Neurobiological Etiology and Treatments without Drugs Tadahiro SHIKIMI 1 Keyword: うつ病 , 神経生物学的病因 , ストレス , 非薬物療法 , depression , neurobiological etiology , stress , treatments without drugs pp.1-5
Published Date 2014/12/31
DOI https://doi.org/10.11477/mf.7009200092
  • Abstract
  • Reference

Abstract

 When stress becomes repetitive and sustained, the ability to stress coping is often impaired, and susceptible individuals in stressful circumstances are at increased risk of developing depression. Impaired stress coping induces hyperactivity of the hypothalamus - pituitary - adrenal axis, proinflammatory cytokine production in the brain and with reduced levels of brain-derived neurotrophic factor regulating neuronal survival, growth and differentiation. These changes are involved in depression development. Physical exercise, appropriate sunlight exposure and useful diet intake are beneficial treatments without drugs for alleviation of stress-related depression.

 The topics in this article were briefly reviewed based on recent reports.


Copyright © 2014, Japan Society of Nursing and Health Care All rights reserved.

基本情報

13452606.16.2.jpg
日本看護医療学会雑誌
16巻2号 (2014年12月)
電子版ISSN 印刷版ISSN 1345-2606 日本看護医療学会

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