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Paraneoplastic Syndrome with Sensory Polyneuropathy : A Report on Rehabilitation in Two Cases Rieko Kawada 1 , Yoichiro Aoyagi 1 , Takashi Hiraoka 1 , Takashi Yamanaka 2 , Katsushi Kuniyasu 3 , Akio Tsubahara 1 1Department of Rehabilitation Medicine, Kawasaki Medical School 2Department of Rehabilitation, Takemoto Hospital 3Department of Rehabilitation, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare Keyword: 傍腫瘍性神経症侯群(paraneoplastic syndrome) , 後根神経節(dorsal root ganglion) , 感覚性運動失調(sensory ataxia) , 長期予後(long-term prognosis) , 疲労(fatigue) pp.572-576
Published Date 2009/9/18
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Abstract : We report two cases of paraneoplastic syndrome with sensory polyneuropathy. Case one showed numbness of the upper and lower extremities before a diagnosis of small cell carcinoma was made. Case two showed the same symptoms coincidentally with a recurrence of ovarian cancer. In both cases, Romberg's sign was positive, ataxic gait was noted, and the patient's skill movement was disturbed. Sensory nerve action potentials were not evoked in any of the nerves. Compound muscle action potential and motor conduction velocity were at the lower limits of normal. The neurological abnormalities did not resolve in spite of medical treatments. In these two cases, the loss of sensory neurons due to a lesion of the dorsal root ganglia was suggested. The loss of sensory feedback might lead to muscle weakness and fatigue, so they tend to be disused. For long-term rehabilitation management in these two cases, we suggested a regular exercise program to prevent muscle weakness.


Copyright © 2009, The Japanese Association of Rehabilitation Medicine. All rights reserved.

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電子版ISSN 印刷版ISSN 1881-3526 日本リハビリテーション医学会

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