Physiology in patients after a stroke Daisuke IKECHI 1 , Susumu YAMASHITA 1 1Department of Emergency Medicine Tokuyama Central Hospital pp.11-17
Published Date 2020/1/1
DOI https://doi.org/10.11477/mf.3102200704
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Fever in patients after a stroke without infection is called neurogenic fever or centrally mediated fever, and is often observed. Injury of the thermoregulatory center in the hypothalamus raises the body temperature. Hemorrhage in the cerebrospinal fluid space leads to production of prostaglandin E2 which causes a physiological temperature increase. Acute cardiac dysfunction in patients after stroke is also often observed. Abnormal reactions of the autonomic nerves and catecholamine surges can cause myocardial damage. The risk of myocardial damage is high if the insular cortex was damaged. The pathophysiological mechanisms of vasospasm with subarachnoid hemorrhage have not yet been elucidated. Delayed cerebral ischemia is caused not only by major cerebrovascular spasm, but also by microcirculatory disorders and other factors.

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