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Japanese

FLUORESCEIN LEAKAGE MEASUREMENT FOR CAPILLARY PERMEABILITY OF HUMAN NASAL MUCOSA Harumi Suzaki pp.15-20
Published Date 1980/1/20
DOI https://doi.org/10.11477/mf.1492209022
  • Abstract
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 Measurement for capillary permeability of human nasal mucosa was studied by using intravenous injection of fluorescein in 11 healthy subjects, in six with allergic rhinitis and in one who received vidian neurectomy.

 The method applied was as follows ; small pieces of filter paper were placed on the inferior turbinates and the septum, and were removedfor measurement at 30 minutes after i.v. administration of 10 ml of 10% fluorescein sodium. The filter papers were put in 1. 0ml of phosphate buffer at pH 7.4, and kept cool and dark place for over 2 hours. Fluorescein concentration in this solution was measured with slitlamp microphotometer.

 As the results, fluorescein leakage from the nasal capillary was more significantly in the subjects with allergic rhinitis than in the healthy subjects. This is the first paper reporting fluorescein leakage measurement for capillary permeability of human nasal mucosa.


Copyright © 1980, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 印刷版ISSN 0386-9679 医学書院

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