凍結手術が奏効した悪性黒色腫症例

CRYOSURGERY FOR MALIGNANT MELANOMA

　Ⅰ．緒言

　各種治療に抵抗し，口蓋に進展再発した鼻腔原発悪性黒色腫症例に制癌剤動注，放射線治療および凍結手術を併用し良好な腫瘍縮小効果を得た。その効果は主として凍結手術によりもたらされたものと考えられ，悪性黒色腫に対するその有用性を痛感した。そこで本例の臨床経過の概略を紹介し，治療方法を中心として若干の文献的考察を加えて報告する。

　Cryosurgery was used successfully in the treatment of a 66-year-old man with recurrent malignant melanoma of the left nasal cavity invaded to the palate after various modes of therapies were attempted. The recurrent and invaded massive tumor was sufficiently responded to the cryosurgery and completely disappeared. Finally,the patient died of liver metastasis without evidence of the disease at primary site 1 year and 5 months after the initial treatment. It is proposed that cryosurgery should be used as alocal therapy concurrently with other antineoplastic aids to obtain good results in the treatment of mucosal malignant melanoma.