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中耳炎殊に慢性化膿性中耳炎に対する治療に関しては古くから色々と論議され,所謂乾燥療法,耳洗法或は近時スルフアミン剤,ペニシリン等の使用に依る化学療法等何れも各々効果ある治療法である.何れにしても慢性化膿中耳炎の治療の目的は如何にして早く,如何にして安價に現存する耳漏を止めるかと云う所にあると思う.私は今回,含硫黄アミノ酸であるヒスチン製剤の注射藥パニールチンの分與を受ける機会を得たので,主として慢性化膿性中耳炎の保存的療法の1つとして実施しその効果を檢討し次の成績を得たのでその概要を報告する.
Naito reports that, for treatment of otitis media, particularly its chronic counterpart, his experience in the use of "panilutin ", a drug of histamine base, has been quite favorable which is shown with results as follows: Among 10 patients who were treated, with 14 ears, the number that was cured were 6 with 10 ears or 71.4 per cent ; those in whom the results proved indefinite numbered 3 patients and with 3 ears or 21.4 per cent. There were some, who had been previously subjected to sulfadrug therapy without appreciable dimunition of aural dis-charges, who, when placed under the present form of treatment, showed a marked response and final cure. The author believes that, the mechanism of this therapy, which appears to be effective in curing chronic ear affections, in majority of cases, is very likely due to active. leucocytic phagocytosis with the number of leucocytes largely increased by the action of histamine on hematopoietic tissues and the general building up of bodily resistance against invasive organisms by token of that same hista-minic action.
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