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Intra-and Extracranial Chondrosarcoma Toshihide TANAKA 1 , Satoshi TANI 1 , Shigehiro NAKAHARA 1 , Takuo HASHIMOTO 1 , Shinichiroh USHIGOME 2 1Department of Neurosurgery, The Jikei University School of Medicine 2The First Department of Pathology, The Jikei University School of Medicine Keyword: Chondrosarcoma , MRI , Vimentin , Combined translabyrinthine approach pp.145-150
Published Date 1995/2/10
DOI https://doi.org/10.11477/mf.1436900978
  • Abstract
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A 17-year-old female, who had diplopia and progres-sive gait disturbance, had been diagnosed as having a right parasellar mass lesion in 1986. Initial CT scan failed to show a parasellar space occupying lesion, al-though it was well demonstrated on MRI. No surgery was carried out at that time.

Seven years later, she was hospitalized because of progressive gait disturbance, lower cranial nerves palsy, and cerebellar sign as well as the known right abdu-cence palsy. At this time, CT scan exhibited a huge low density area with a marginal high density area sug-gesting calcification, which extended from the right pa-rasellar area to the ventral portion of the midbrain. She underwent surgery under the diagnosis of cartilaginous tumor or chordoma. The intracranial lesion was re-moved via combined translabyrinthine approach and epidural subtemporal approach. The tumor was hitolo-gically diagnosed as well-differentiated chondrosarco-ma. Electron-microscopy demonstrated tumor cells with features of chondrocytes.

Since the original site of the tumor, strategies for treatment and prognosis are different from each other, distinction between chondrosarcoma and chordoma is important. MRI seemed very useful for making this dis-tinction as a first step.


Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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