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A Case of a Solitary Plasmacytoma Extending into the Extradural Space Hiroshi NAKANO 1 , Koichi KATO 1 , Shunsuke NOMURA 1 , Masanori NAKAGAWA 1 , Takashi HIGA 1 , Shigeru KADOYAMA 1 , Takakazu KAWAMATA 2 , Hiroshi UJIIE 1 , Akira TERAMOTO 1 1Department of Neurosurgery, Tokyo Rosai Hospital 2Department of Neurosurgery, Tokyo Women's Medical University Keyword: plasmacytoma , primary extradural meningioma , multiple myeloma pp.811-817
Published Date 2017/9/10
DOI https://doi.org/10.11477/mf.1436203598
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 Plasmacytomas are characterized by a monoclonal proliferation of plasma cells, and constitute the bulk of multiple myeloma. A solitary plasmacytoma is a rare entity, and is even more unlikely to occur intracranially. Here we present a 62-year-old man with an intracranial tumor. Magnetic resonance imaging revealed a large mass on the surface of the right fronto-parieto-temporal region, with extradurally directed growth. The tumor was enhanced homogenously by gadolinium, with dural tail-like findings, which resembled a meningioma. Head computed tomography scan showed osteolytic changes of the calvarium. Tumor removal following intravascular embolization was performed. The tumor seemed to have developed from the dura mater because it was firmly adhered to the dura but not to the calvarium. Histopathological analysis revealed monoclonal proliferation of plasma cells, which were positive for CD56, CD138, and lambda chain, on immunostaining. Since a systemic examination showed no evidence of other lesions, we diagnosed the tumor as a solitary dural plasmacytoma. There was no recurrence after postoperative radiotherapy. Rare entities, such as a solitary plasmacytoma, should be considered when an intracranial lesion with atypical radiological features is observed. If the lesion is anatomically resectable, histopathological evaluation is essential.


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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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