雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Clinical Evaluation on Glucocorticoid Administration in the Neurosurgical Patients (the Third Report):Serial Plasma Cortisol Assay following Betamethasone 8mg Intravenous Injection Hisanori YOSHIMOTO 1 , Shintaro MORI 1 , Shigejiro MATSUMURA 1 , Masahiro OHTA 1 , Shiro KAJIWARA 1 , Shuichi OKI 1 , Hiromichi HIBINO 1 , Susumu ISHIKAWA 1 , Tohru UOZUMI 1 , Keishi MATSUMOTO 2 1Department of Neurosurgery, Hiroshima University School of Medicine 2Institute for Cancer Research, Osaka University Keyword: Cortisol , Betamethasone , Glucocorticoid , Brain edema pp.1247-1251
Published Date 1977/11/10
DOI https://doi.org/10.11477/mf.1436200723
  • Abstract
  • Look Inside

The effect of betamethasone on plasma cortisol concentrations was studied in 6 healthy adult men. Each of them was administered 8mg of betamethasone in a single intravenous injection. Blood samples were obtained serially for 2 days before the injection of betamethasone and for a week after the injection. Plasma cortisol was measured by competitive protein binding analysis. Before the injection of betamethasone plasma cortisol levels showed the normal diurnal rythm in all the cases. After the injection plasma cortisol levels decreased rapidly and a mean half life time was about 1.7 hours.


Copyright © 1977, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

関連文献

もっと見る

文献を共有