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Neuropathology of locus ceruleus. Masanori TOMONAGA 1 1Department of Neuropathlogy, Institute of Brain Research, University of Tokyo pp.328-337
Published Date 1986/4/10
DOI https://doi.org/10.11477/mf.1431905785
  • Abstract
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Locus ceruleus is a brainstem nucleus which consists of melanin containing nerve cells. The number of nerve cells decrease markedly in the elderly persons with age. Changes of locus ceruleus may be responsible for various autono-mic dysfunctions including sleep disturbance. Several pathological changes, e.g. neuro-fibrillary tangles and Lewy bodies, appear in the phy-siological condition in the aged brains. Locus ceruleus is affected in various neurological dis-eases, particularly in Parkinson's disease, multiple system atrophy, progressive supranuclear palsy and senile dementia of Alzheimer's type.


Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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