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Gating of signal flow in the hippocampus Yuko SEKINO 1,2 , Tomoaki SHIRAO 1,2 1Department Neurobiology and Behavior, Gunma University School of Medicine 2CREST Keyword: memory , hippocampus , the CA2 region , adenosine pp.283-296
Published Date 2001/4/10
DOI https://doi.org/10.11477/mf.1431901244
  • Abstract
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In this article, we first review the classical concepts for the hippocampal network, such as the trisynaptic circuit and the lamellar hypothesis, and summarize recent results which highlighting the underappreciated role of the CA2 region. Second, we propose the novel concept that memory information is stored efficiently only when the brain is in appropriate state for memory acquisition. This state, which we call the motivating state for memory, is determined by the levels of awareness, cognition, attention, emotion and other influences.


Copyright © 2001, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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