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Japanese

Endothelial cell in a microcirculation from a viewpoint of arachidonic acid cascade. Masaharu TSUCHYA 1 , Iwao KUROSE 1 , Hidekazu SUZUKI 1 1Department of Internal Medicine, School of Medicin, Keio University pp.883-888
Published Date 1992/12/10
DOI https://doi.org/10.11477/mf.1431900283
  • Abstract
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I believe that the investigation of microcirculation should be conducted with regard to the interrelationship of four elements, namely, blood flow, vessel wall (endothelial cells, pericytes etc.), cellular components in the vessels (platelets, leukocytes, erythrocytes etc.) and extravascular tissues (mast cells etc.). The recent biochemical, molecular and biological advances enabled us to explain their interaction by mediating many kinds of factors. If there is any damage to the vessels, the arachidonic acid cascade will be activated followed by the production of prostaglandins. It is very important for us to take into account the arachidonic acid metabolism in endothelial cells and the cell to cell interaction in a microcirculation.


Copyright © 1992, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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