Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
- 参考文献 Reference
パーキンソン病(PD)は,遂行機能障害,注意障害,視空間認知障害,記憶障害,社会的認知障害などの認知機能障害をきたすことが明らかになっている。これらの認知機能障害はPD患者の予後やQOLに大きな影響を与えるため,その診断,危険因子,病理学的背景,発症機序,治療法についての研究が行われ,知見が年々増している。今後,PD診療では認知機能障害も運動症状とともに治療が展開することを念頭に置き,PDの認知機能障害を概説する。
Abstract
Parkinson's disease (PD) patients can present with cognitive impairment, such as deficits in attention and memory processes, visual perception, executive function and social cognition. These dysfunctions negatively affect the activities of daily living and outcome of patients. Some of the risk factors, pathological background and etiology of cognitive dysfunction in PD with dementia (PDD) have been determined. Treatments for such dysfunctions are attracting much attention. Some medications, such as donepezil, rivastigmine, and memantine, have shown to improve motor and/or cognitive functions. Cognitive impairment and motor symptoms in PD can be treated concurrently. Therefore, the correlation between motor and cognitive function should be considered when treating PD.
Copyright © 2019, Igaku-Shoin Ltd. All rights reserved.