BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 71, Issue 8 (August 2019)

Diagnosis and Treatment of Cognitive Impairment in Parkinson's Disease Tomotaka Shiraishi 1 , Hidetomo Murakami 1 , Yasuyuki Iguchi 1 1Department of Neurology, The Jikei University School of Medicine Keyword: パーキンソン病 , 認知症 , MCI , ドネペジル , メマンチン , リバスチグミン , Parkinson's disease , dementia , mild cognitive impairment , donepezil , memantine , rivastigmine pp.869-874
Published Date 2019/8/1
  • Abstract
  • Look Inside
  • Reference


Parkinson's disease (PD) patients can present with cognitive impairment, such as deficits in attention and memory processes, visual perception, executive function and social cognition. These dysfunctions negatively affect the activities of daily living and outcome of patients. Some of the risk factors, pathological background and etiology of cognitive dysfunction in PD with dementia (PDD) have been determined. Treatments for such dysfunctions are attracting much attention. Some medications, such as donepezil, rivastigmine, and memantine, have shown to improve motor and/or cognitive functions. Cognitive impairment and motor symptoms in PD can be treated concurrently. Therefore, the correlation between motor and cognitive function should be considered when treating PD.

Copyright © 2019, Igaku-Shoin Ltd. All rights reserved.


BRAIN and NERVE-神経研究の進歩
71巻8号 (2019年8月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院