サルコイドーシスの皮膚病変

Cutaneous Lesions of Sarcoidosis

サルコイドーシスの皮膚病変は多彩で，特異的病変の皮膚サルコイド，異物が存在する瘢痕浸潤，非特異的病変の結節性紅斑に大別される。皮膚病変は他臓器病変より組織採取しやすいため，サルコイドーシスの確定診断に重要な病変である。発症頻度は結節型および局面型皮膚サルコイドと瘢痕浸潤が高く，皮膚サルコイドは顔面に，瘢痕浸潤は膝蓋・肘頭に好発する。微小な病変のこともあり，同部の丁寧な診察が肝要である。

Abstract

Cutaneous lesions of sarcoidosis show varied clinical features. They are categorized into specific types; skin sarcoid, scar infiltrations with granulomas and foreign bodies, and non-specific lesions like erythema nodosum. Identification of the cutaneous lesions is important for the diagnosis of sarcoidosis, because they are an easily accessible source of tissue for histologic examination. The commonest cutaneous lesions in sarcoidosis are the nodular and plaque types of skin sarcoid, and scar infiltrations. Since the preferential sites for skin sarcoid and scar infiltrations are the face and knees, respectively, these areas should be carefully examined.