BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 71, Issue 4 (April 2019)

Skin Manifestations of Vasculitis Naoko Ishiguro 1 1Department of Dermatology, Tokyo Women's Medical University Keyword: 血管炎 , 皮膚病変 , 触知性紫斑 , リベド , 小型血管炎 , 中型血管炎 , vasculitis , skin manifestations , palpable purpura , livedo , small vessel vasculitis , medium vessel vasculitis pp.339-344
Published Date 2019/4/1
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Skin symptoms that might indicate vasculitis include palpable purpura, blisters, skin ulcers, livedo, and subcutaneous nodules. Palpable purpura, livedo, and subcutaneous nodules are particularly important; the first correlates with small vessel vasculitis, and the latter two with medium vessel vasculitis on histopathology. If the presence of deep lesions, as seen in cases of livedo and subcutaneous nodules are suspected, the skin biopsy must include fat tissue from the active skin lesions to arrive at the accurate histological diagnosis. Differential diagnoses should be considered based on the size of the most heavily impacted vessels, to determine the type of vasculitis. The diagnosis and treatment of vasculitis requires cooperation between the Nephrology, Neurology, Respiratory Medicine, Rheumatology, Dermatology, and Pathology Departments.

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BRAIN and NERVE-神経研究の進歩
71巻4号 (2019年4月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院