BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 70, Issue 11 (November 2018)

FMRI Neurofeedback and its Application to Psychiatric Disorders Keima Tose 1 , Yujiro Yoshihara 2 , Hidehiko Takahashi 1 1Department of Psychiatry, Kyoto University Graduate School of Medicine 2Human Brain Research Center, Kyoto University Graduate School of Medicine Keyword: fMRIニューロフィードバック , 統合失調症 , うつ病 , 注意欠如・多動症 , 強迫症 , fMRI neurofeedback , schizophrenia , depression , attention-deficit/hyperactivity disorder , obsessive-compulsive disorder pp.1209-1216
Published Date 2018/11/1
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Functional magnetic resonance imaging (fMRI) neurofeedback can train subjects to control their brain activity with real-time processing and high spatial resolution, as many advances in MRI data acquisition methods, computer hardware, and processing algorithms have improved the sensitivity and speed of fMRI neurofeedback. FMRI neurofeedback has been applied to psychiatric disorders, including schizophrenia, major depressive disorder, attention-deficit hyperactivity disorder, and obsessive-compulsive disorder. Some studies reported that fMRI neurofeedback improved the symptoms of patients with psychiatric disorders, although it remains unclear if the regulation of the targeted brain regions or the functional connectivities themselves improved the symptoms. It is necessary that researchers pay enough attention to their study's design, because many non-specific factors such as introduction, mental strategies, self-efficacy, attention, motivation, learning ability, and reward influence the results in fMRI neurofeedback studies. If the long-term effect of fMRI neurofeedback on the symptoms of psychiatric disorders are recognized, fMRI neurofeedback will be useful in treating heterogeneous patients with psychiatric disorders without side effects.

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BRAIN and NERVE-神経研究の進歩
70巻11号 (2018年11月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院