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Autoantibodies in Neuromyelitis Optica Spectrum Disorders Ichiro Nakashima 1 , Tetsuya Akaishi 2 1Department of Neurology, Tohoku Medical and Pharmaceutical University 2Department of Neurology, Yonezawa National Hospital Keyword: 視神経脊髄炎 , アクアポリン4 , ミエリンオリゴデンドロサイト糖蛋白 , 多発性硬化症 , 自己抗体 , neuromyelitis optica , aquaporin-4 , myelin oligodendrocyte glycoprotein , multiple sclerosis , auto-antibody pp.297-304
Published Date 2018/4/1
DOI https://doi.org/10.11477/mf.1416201003
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Abstract

Neuromyelitis optica was previously considered a subtype of multiple sclerosis until a specific serum antibody, NMO-IgG, was discovered in 2004. In 2012, anti-MOG antibody was found specifically in the serum of patients whose presentation was similar to those with neuromyelitis optica. These autoantibodies are pathogenic and are important disease markers when reaching a diagnosis.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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