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Therapeutic Strategies for Neuromyelitis Optica Ichiro Nakashima 1 1Division of Neurology, Department of Medicine, Tohoku Medical and Pharmaceutical University Keyword: インターロイキン6 , 補体 , B細胞 , アクアポリン4 , モノクローナル抗体 , interleukin-6 , complement , B cells , aquaporin-4 , monoclonal antibody pp.493-497
Published Date 2023/5/1
DOI https://doi.org/10.11477/mf.1416202364
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Abstract

Treatments for acute attacks of neuromyelitis optica (NMO) include steroid pulse therapy, plasma exchange, and intravenous immunoglobulin. Oral immunosuppressants, such as prednisolone and azathioprine, have also been used to prevent relapse. Recently, biologic agents such as eculizumab, satralizumab, inebilizumab, and rituximab have been approved for use in Japan. Although side effects caused by steroid therapy have been issues for patients in the past, active use of the newly approved biologics is expected to help patients avoid the adverse effects of steroids and improve their qualities of life.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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