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Association between Multiple Sclerosis or Neuromyelitis Optica and Epstein-Barr Virus Masahiro Mori 1 1Department of Neurology, Graduate School of Medicine, Chiba University Keyword: 多発性硬化症 , 視神経脊髄炎 , EBウイルス , 抗アクアポリン4抗体 , 慢性活動性EBウイルス感染症 , multiple sclerosis , neuromyelitis optica , Epstein-Barr virus , anti-aquaporin-4 antibody , chronic active Epstein-Barr virus infection pp.881-890
Published Date 2015/7/1
DOI https://doi.org/10.11477/mf.1416200227
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Abstract

Accumulated evidence shows an association between Epstein-Barr viral (EBV) infection and multiple sclerosis (MS). In particular, EBV infections before the onset of MS, particularly in childhood, is associated with the pathogenesis of MS. Meanwhile, the association between neuromyelitis optica (NMO) and infectious agents has been reported, but is currently unclear. Recently we studied the association between NMO and EBV and compared between MS and EBV. The results showed that MS is associated with past infections of EBV as the results of previous studies. In contrast, NMO is associated with the reactivation of EBV.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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