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MR-Guided Focused Ultrasound Hideki Mochizuki 1 , Noriaki Hattori 1,2 1Department of Neurology, Osaka University Graduate School of Medicine 2Endowed Research Department of Clinical Neuroengineering, Global Center for Medical Engineering and Informatics, Osaka University Keyword: MRガイド下集束超音波治療 , 本態性振戦 , 視床中間腹側核 , Vim核 , 視床破壊術 , パーキンソン病 , MR-guided focused ultrasound , MRgFUS , essential tremor , ventrolateral nucleus(VL) of the thalamus , thalamotomy , Parkinson's disease pp.147-153
Published Date 2018/2/1
DOI https://doi.org/10.11477/mf.1416200967
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Abstract

Since the middle of the 20th century and in order to treat neurological diseases, clinicians have proposed the use of ultrasound, instead of skin incision or trepanation, when performing intracranial thermocoagulation. However, focusing ultrasound intracranially with high precision was technically difficult until recent technological developments. Specifically, advancements in ultrasound phased-array transducers have eliminated the need for a craniotomy, and progress in magnetic resonance (MR) imaging has allowed the real-time measurement of intracranial temperature. Both of the above have enabled the use of MR-guided focused ultrasound as a treatment for refractory essential tremor. Studies focusing on the long-term effects of this treatment are under way. Given that it is less invasive than previous methods, this procedure could be indicated for the treatment of other neurological diseases, including Parkinson's disease, brain tumors, dystonia, and epilepsy.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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