Apathy and Dementia Kazunori Okada 1 , Shuhei Yamaguchi 2 1Oda Silverclinic 2Department of Neurology, Shimane University Keyword: 認知症 , アパシー , 先駆症状 , 行動心理症状 , やる気スコア , dementia , apathy , prodromal syndrome , behavioral and psychological symptoms (BPSD) , apathy scale pp.767-778
Published Date 2016/7/1
DOI https://doi.org/10.11477/mf.1416200509
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Apathy, which has been attracting attention since Marin's report in 1990, is ubiquitous among neuropsychiatric diseases. It has a major impact on the quality of life in both patients and their caregivers and impairs rehabilitation and outcome. Furthermore, apathy is important as a prodromal syndrome in the development of dementia in mild cognitive impairment (MCI). We reviewed the neurobiological basis, prevalence and assessment of potential benefits of non-pharmacologic and pharmacologic interventions for apathy in MCI and dementia.

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