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Sleep Problem as a Prodrome and Risk Factor for Dementia Kazuo Mishima 1 1Department of psychophysiology, National Institute of Mental Health, National Center of Neurology and Psychiatry Keyword: 認知症 , 睡眠障害 , 概日リズム障害 , 前駆症状 , リスク要因 , dementia , sleep disorder , circadian rhythm disorder , prodrome , risk factor pp.779-791
Published Date 2016/7/1
DOI https://doi.org/10.11477/mf.1416200510
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Abstract

Dementia, including Alzheimer's disease, is often associated with various sleep disorders such as insomnia, hypersomnia, circadian rhythm sleep disorders, sleep-disordered breathing and sleep debt due to organic damages of sleep/wake-promoting nucleus and circadian center (suprachiasmatic nucleus). These sleep disorders reduce the quality of life of individuals with dementia, and increase the care burden, which are major social issues. Recent studies have revealed that sleep deterioration is not only a comorbid symptom but also a prodrome and a risk factor for the development of dementia.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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