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A case of adenosquamous carcinoma of the prostate with rapid progression during hormone therapy Shuichiro Kobayashi 1 , Masataka Yano 1 , Akio Komatsu 2 , Satoshi Kitahara 1 Keyword: 前立腺 , 腺扁平上皮癌 pp.657-660
Published Date 2018/7/20
DOI https://doi.org/10.11477/mf.1413206342
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Abstract

Adenosquamous carcinoma of the prostate is a rare histological variant with clinical aggressive form of prostate cancer. A 78-year-old man was incidentally found to have right hydronephrosis and lymph node swelling in pelvic floor by computed tomography. The serum prostate-specific antigen (PSA) level was 164.41 ng/mL. Transperineal prostate biopsy revealed a Gleason score 8 (4 + 4) prostatic adenocarcinoma. Although he was treated with combined androgen deprivation therapy with good PSA response, perineal pain had appeared 4 months later. Magnetic resonance imaging revealed enlarged prostate heterogeneous mass of 10cm in diameter which was compressing the rectum. Transrectal needle biopsy of the tumor showed squamous cell carcinoma, and he was finally diagnosed as adenosquamous carcinoma of the prostate (Rinsho Hinyokika 72 : 657-660, 2018).


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電子版ISSN 1882-1332 印刷版ISSN 0385-2393 医学書院

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