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Small cell carcinoma of prostate coexisting with carcinoid:A case report Tatsuaki Onuki 1,5 , Kiyoshi Fujinami 1 , Yutaka Senga 1 , Jinyu Sano 2 , Akihiko Goto 3 , Tomoyuki Asakura 4 1Department of Urology,Chigasaki City Hospital 2Department of Pathology,Chigasaki City Hospital 3The Goto Clinic 4The Asakura Hospital Keyword: 前立腺癌 , カルチノイド腫瘍 , 小細胞癌 pp.593-596
Published Date 2011/7/20
DOI https://doi.org/10.11477/mf.1413102445
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We report a rare case of small cell carcinoma(SCC)coexisting with carcinoid of prostate. A 78-year-old man with a chief complaint of dysuria and macrohematuria underwent a transurethral resection of the prostate(TURP)at another hospital. Although the prostate specific antigen was 5.2 ng/ml,histological diagnosis was poorly differentiated adenocarcinoma with a Gleason's score of 5+4(T3aN0Mx). After 3 months of maximum androgen blockade,he was admitted to our hospital because of urinary retension with macro-hematuria. We performed transurethral coagulation and TURP because of the repeated bladder tamponade. The immunohistochemical examination of specimens revealed both SCC and carcinoid. Abdomino-pelvic CT showed an enlarged prostate and distant metastasis. Radiotherapy resulted in a great reduction of the tumor volume,but chemotherapy(docetaxel)was ineffective. He developed multiple distant metastasis and died of disease 7 months after the diagnosis.


Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1332 印刷版ISSN 0385-2393 医学書院

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