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Small cell carcinoma of the prostate diagnosed with the bladder invasion that appeared during maximum androgen blockade therapy Yusuke Oyama 1 , Hironobu Okugi 1 , Hiroshi Okazaki 1 , Toshiyuki Nakamura 1 , Misa Iijima 2 1Department of Urology,Tatebayashi Kousei Hospital 2Department of Pathology,Gunma Prefectural Cancer Center Keyword: 前立腺癌 , 小細胞癌 pp.659-663
Published Date 2010/8/20
DOI https://doi.org/10.11477/mf.1413102098
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A 72-year-old man treated with maximum androgen blockade therapy for a moderately differentiated prostate adenocarcinoma〔T1cN0M0,stageB0,prostate specific antigen(PSA)79.417 ng/ml,Gleason score 4+5〕developed gross hematuria 1 year and 10 months after the beginning of the treatment. His serum PSA levels remained stable(1~2 ng/ml). Cystoscopy disclosed the bladder invasion and histologically diagnosed as small cell carcinoma. PSA was 1.552 ng/ml,and neuro-specific enolase(NSE)was 220 ng/ml(0~10 ng/ml). He received 8 courses of chemotherapy consisting of etoposide and cisplatin(EP)which has achieved partial remission of the bladder tumor.


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電子版ISSN 1882-1332 印刷版ISSN 0385-2393 医学書院

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