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I.はじめに
本症は1948年MiescherおよびLeder1)により初めて記載されたもので,欧米においても比較的稀らしい疾患とされるが,本邦においては1960年,第383回日本皮膚科学会東京地方会において東大より患者供覧された1例2)および1964年の吉田等3)の報告例があるにすぎず,極めて稀れな疾患と考えられる。我々は最近,本症の1例を経験したのでここにその概略を報告する。
This disease and necrobiosis lipoidica diabeticorum should belong to the same entity, though histologic differentiation between them are possible.
A 44-year-old housewife have had discoid, atrophic, yellow-reddish plaques on the scalp and thigh.
Histologic specimen showed non-specific chronic granuloma accompanied by infiltration of lymphocytes, epitheloid cells and giant cells throughout the dermis and subcutaneous tissue. There were swelling, necrosis and fragmentation of collagen around the infiltration, but no lipid deposition was found between the fibers.There were thickning of wall or obliteration of the small vessels in some parts.
There was no abnormality in glucose level of urine and blood. The results of laboratory tests were within normal limits except increased level of IgA, IgG and 2-Macroglobulin of serum.
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