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A Case with Extramedullary Plasmacytoma of Paranasal Sinus Yoshihumi Uno 1 1Department of Otolaryngology, Okayama Saiseikai General Hospital pp.1048-1051
Published Date 1995/11/20
DOI https://doi.org/10.11477/mf.1411901266
  • Abstract
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A 93-year-old male presented with a bulky exten-sive tumor occupied in the left maxillary antrum with bony invasion including the orbital floor. The tumor was histologically diagnosed as extramedui-lary plasmacytoma.

Irradiation therapy was employed as the primary treatment of choice because of his advanced age and locally extensive disease, but the tumor was radio-resistant and developed metastatic spread to the bilateral parotid glands and abdominal wall without systemic myelomatous lesions.

The patient received combination chemotherapy by melphalan and prednisolone (M-P) for dis-seminated disease with good response, which was later confirmed by postmortem examinations.

We emphasize that combination chemotherapy should be added as another modality of treatment for this disease to surgery and radiation, either alone or in combination.


Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1316 印刷版ISSN 0914-3491 医学書院

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