頬部平滑筋肉腫の1例

Leiomyosarcoma of the Cheek : Report of a case

はじめに

　平滑筋肉腫はその発生由来として，血管中膜，間葉系未分化細胞および腺組織筋上皮細胞などが挙げられる。その発生部位も体内のすべての領域にわたっている。比較的発生頻度が高い器官としては子宮および消化管が挙げられているが，頭頸部領域原発のものは稀である^1〜4）。今回，我々は頬部に発生した平滑筋肉腫の1例を経験する機会を得たので頭頸部領域における平滑筋肉腫の文献的考察を加えて報告する。

Leiomyosarcoma originated from head and neck region is rarely encountered and 43 cases have been reported in the literature. Only five cases of them (including our case) are derived from the cheek.

The pathological diagnosis, behavior, therapy and prognosis as to these 43 cases are discussed. Surgical removal is still the first choice for treat-ment since effectiveness was rarely seen in che-motherapy and radiotherapy. Also in the case with cervical metastasis, neck dissection in the early stage is considered to produce better prog-nosis.

For better strategy for management of this disease, accumulation of data and further progress in chemotherapy should be required.