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Therapy-related myelodysplastic syndrome after chemoradiotherapy for oropharyngeal cancer: A case report Taisei Kato 1 , Munenaga Nakamizo 1 , Kazuhiko Yokoshima 1 , Shunta Inai 1 , Atsuko Sakanushi 1 , Azusa Sakai 1 , Masashi Nakaishi 1 , Nobuhiro Usukura 1 , Kimihiro Okubo 1 1Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Nippon Medical School pp.181-187
Published Date 2020/2/20
DOI https://doi.org/10.11477/mf.1411202304
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 It is well known that chemotherapy and radiotherapy performed for the treatment of malignant tumors can induce therapy-related myelodysplastic syndrome(t-MDS). We herein describe our experience of a case of a 65-year-old male patient who developed t-MDS after treatment of advanced oropharyngeal cancer. Just after induction chemotherapy and concurrent chemoradiotherapy(CCRT), pancytopenia was diagnosed as t-MDS and not myelosuppression by bone marrow biopsy. Furthermore, we suspected a poor prognosis based on IPSS-R. Thus, pre-treatment evaluation of the risks of t-MDS might be significant but further investigation is needed.


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電子版ISSN 1882-1316 印刷版ISSN 0914-3491 医学書院

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