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原著
浸潤型蝶形骨洞アスペルギルス症に対して蝶形骨洞単洞化手術を施行した1例
A case of invasive fungal sphenoiditis treated by sphenoid drill-out
牧原 靖一郎
1
,
岡野 光博
2
,
石原 久司
1
,
宮武 智実
1
,
津村 宗近
2
,
假谷 伸
2
,
西﨑 和則
2
Seiichiro Makihara
1
,
Mitsuhiro Okano
2
,
Hisashi Ishihara
1
,
Tomomi Miyatake
1
,
Munechika Tsumura
2
,
Shin Kariya
2
,
Kazunori Nishizaki
2
1香川労災病院耳鼻咽喉科・頭頸部外科
2岡山大学大学院医歯薬学総合研究科耳鼻咽喉・頭頸部外科学
1Department of Otorhinolaryngology-Head and Neck Surgery, Kagawa Rosai Hospital
pp.765-770
発行日 2014年8月20日
Published Date 2014/8/20
DOI https://doi.org/10.11477/mf.1411102938
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はじめに
副鼻腔真菌症の大部分は予後が良好な非浸潤型であるが,稀に副鼻腔の骨破壊をきたし,頭蓋内や眼窩内に浸潤し,予後不良となる浸潤型が認められる。今回,浸潤型蝶形骨洞アスペルギルス症に対して蝶形骨洞単洞化手術を施行した1例を経験したので文献的考察を加えて報告する。
We present a 68-year-old man suffered from invasive fungal sphenoiditis. The patient complained of right eye pain and headache. His sphenoiditis was refractory to both medical management of VRCZ and sphenoidotomy, and finally he underwent sphenoid drill-out. After the final surgery, we performed therapeutic drug monitoring(TDM)and managed the internal use of VRCZ thoroughly. After a year, he has been doing well. When the clinical response is poor, or side effects are developed, measurement of the TDM is important as a tool of medical management.
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