顎下腺原発多形腺腫由来筋上皮癌の1例

A case of carcinoma ex pleomorphic adenoma in the submandibular gland from which myoepithelial carcinomas have arisen with cervical and lung metastases

Ⅰ．はじめに

　多形腺腫由来癌（carcinoma ex pleomorphic adenoma）は，唾液腺原発の多形腺腫の上皮性または筋上皮性成分が長い経過で癌化したものであり，多くは腺癌や未分化癌，唾液腺導管癌である。筋上皮癌の発生および肺転移の報告はきわめて稀で，顎下腺における報告はいまだみられない。

　今回われわれは，顎下腺多形腺腫由来癌が筋上皮癌として頸部再発と肺転移を繰り返した症例を経験したので報告する。

　A 51-year-old female presented with carcinoma ex pleomorphic adenoma in the submandibular gland, from which myoepithelial carcinomas have arisen with cervical and lung metastases. Although complete resection of cervical tumors were performed, she has been suffering from carcinomatous pleurisy.

　This is the first case report in the literatures.