Clinical evaluation of systemic dilazep dihydrochloride for diabetic retinopathy Mikinori Yuguchi 1 1Dept of Ophthalmol, Nagoya City Univ Med Sch pp.1213-1216
Published Date 1997/6/15
DOI https://doi.org/10.11477/mf.1410908865
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We treated 14 cases (28 eyes) of simple or preproliferative diabetic retinopathy by peroral dilazep dihydrochloride at the daily dosis of 300 mg. The efficacy was evaluated using visual acuity, fundus and fluorescein angiographic findings as parameters. At one year after treatment, retinopathy improved in 32% and deteriorated in 25%. At three years after treatment, retinopathy improved in 25% and deteriorated in 46%. In the control group of 12 cases (24 eyes), retinopathy improved in 15% and deteriorated in 45% at one year. It improved in 15% and deteriorated in 70% at 3 years. There was no significant difference between the two groups. The lower rate of deterioration in the treated group appeared to show the beneficial effect of treatment.

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