糖尿病黄斑浮腫発生に対する硝子体の役割

Role of the vitreous in the development of diabetic macular edema

　黄斑浮腫発生に対する硝子体の役割を明らかにするために，重回帰分析を用いて糖尿病網膜症を認める糖尿病患者283例283眼（黄斑浮腫は45眼）を検討した。その結果，糖尿病の推定罹病期間が長く，黄斑部硝子体が未剥離な症例において黄斑浮腫発生の危険性が高いことが明らかとなった。黄斑部硝子体未剥離が糖尿病黄斑浮腫の発生に影響を与える可能性が示唆された。

To identify the role of the vitreous in the development of diabetic macular edema, we reviewed 283 eyes of 283 patients with diabetic retinopathy. Macular edema was present in 45 eyes. Multiple linear regression analysis, duration of diabetes mellitus and absence of vitreomacular separation were positively associated with the development of macular edema. Absence of posterior vitreous detachment in the posterior fundus was thus identified as one of the underlying causes of diabetic macular edema.