緑内障眼におけるhigh-pass resolution perimetryのneural capacityと網膜神経線維層厚

Retinal nerve fiber layer thickness and neural capacity by high-pass resolution perimetry in glaucoma

（26D-7）　原発開放隅角緑内障（POAG）または正常眼圧緑内障（NTG）24例48眼において，high-passresolution perimetry （HRP）によりneural capacity （NC）を測定し，スキャニングレーザーポラリメーターにより視神経乳頭周囲の網膜神経線維層（NFL）厚を測定した。同一症例のNCの左右差とNFL厚の左右差の間に統計学的に有意な相関があった（n＝24,r＝0.47,p＝0.02）。POAGではNCの左右差とNFL厚の左右差の間に有意な相関があったが，NTGでは両パラメーター間に有意な相顕はなかった。スキャニングレーザーポラリメーターで測定したNFL厚の左右差と，HRPで測定した網膜神経節細胞と神経線維の機能状態（NC）の左右差との間の相関の程度は，POAGとNTGでは異なる可能性がある。

We measured the neural capacity as determined by high-pass resolution perimetry in 48 eyes of 24 patients with primary open-angle glaucoma (POAG) or normal-tension glaucoma. These eyes were also evaluated for the thickness of retinal nerve fiber layer (NFL) by means of a confocal scanning laser polarimeter. There was a significant correlation between the interocular differences in neural capacity and those in NFL thickness (n =24, r = 0.47, p= 0.02). A significant correlation was present between the two parameters in eyes with POAG but not in those with normal-tension glaucoma. The findings show the potential differences between POAG and normal-tension glaucoma regarding the relation between NFL thickness on the one hand and the number of functional retinal ganglion cells and nerve fibers on the other.