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(D−7PM−5) 緑内障における網膜神経線維層(RNFL)厚と静的視野との相関性について検討した。対象は正常者6例6眼,高眼圧症患者7例7眼,緑内障患者46例72眼で,光干渉断層計(OCT)による視神経乳頭周囲のRNFL厚を測定し,ハンフリー視野計のプログラム24-2の結果との相関性を調べた。
全象限のmean deviation(MD),mean sensitivity(MS)とRNFL厚との間には非線形的な関係が得られ(r=0.66〜0.68),MDが−5dB以上の視野とRNFL厚の相関性は−5dB未満の視野に比べ弱かった。上下半視野のMSとRNFL厚の関係においても前者の相関性が後者に比べ弱くなったが,早期緑内障視野では視野を細分割してRNFL厚との相関性を調べると,上耳側と下耳側で良好な相関性を示した。RNFL厚と静的視野との間には非線形的な関係がみられた。早期緑内障視野ではRNFL厚との相関性が弱いが,視野を細分割して相関性を調べることが有用であった。
We measured the retinal nerve fiber layer (RNFL) thickness and static visual field in 85 eyes. The series comprised 72 glaucomatous eyes, 7 ocular hypertensive eyes and 6 normal eyes. RNFL was measured by an optical coherence tomography. Program 24-2 by Humphrey Visual Field Analyzer was used to evaluate the mean deviation (MD) and mean sensitivity (MS) for the whole visual field. There was a nonlinear relation (r = 0.66-0.68) between RNFL thickness and MD and between RNFL thickness and MS. There was a lesser correlation between RNFL thickness and whole visual field or hemifield MS in early-stage glaucoma than in moderate or advanced glaucoma. In early-stage glaucoma, the RNFL thickness in supero- and inferotemporal peripaillary sectors was strongly correlated with the visual field in all sectors. The findings show the RNFL thickness to be nonlinearly correlated with the static visual field in moderate and advanced glaucoma. Sectorial division of parapaillary area was usuful in evaluating the early glaucomatous visual field defect.
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