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斜視手術を行った10歳未満の小児12例19眼に,手術翌日から治療の目的で0.1%デキサメタゾンを1日3回点眼し,眼圧の反応を追跡した。点眼開始から最短8日から最長35日目の時点で,13眼が 28mmHg以上,4眼が 21〜27mmHg, 2眼が 20mmHg以下の眼圧を呈した。点眼中止の4週後には,全例で眼圧は21mmHg以下であった。10歳未満の小児は,0.1%デキサメタゾン点眼による眼圧上昇の頻度が高いので,その使用には注意が必要であると結論される。
We measured the intraocular pressure (IOL) in 12 children who underwent surgery for strabismus. All the cases received 0.1% dexamethasone 3 timesstarting on the day after surgery. All were under 10 years of age. Among 19 eyes receiving topical dexamethasone, the IOP was greater than 27mmHg in 13 eyes, between 21 and 27mmHg in 4 and less than 21mmHg in 2 within 5 weeks after surgery. The elevated IOP decreased to 21mmHg or less after discontinuation of dexamethasone. The pre-sent findings suggest a higher incidence of cortico-steroid responder in children under 10 years of age.
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