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Effect of a signal instillation of latanoprost on the quasi-static characteristics of accommodation Naofumi Hirose 1 , Tsuneto Iwasaki 1 , Takaomi Nasu 1 , Kenji Ibi 1 , Akihiko Tawara 1 1Dept of Ophthalmol, Univ of Occup and Environm Health pp.957-960
Published Date 2002/6/15
DOI https://doi.org/10.11477/mf.1410907763
  • Abstract
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We evaluated the effect of instillation of 0.005% latanoprost on the quasi-static characteristics of accom-modation. Ophthalmologically normal 22 eyes of 11 persons served as test subjects. Their ages averaged 19.3±2.1 years. We used instillation of physiolocial saline as control. Twelve hours after a single instillation of latanoprost,the intraocular pressure decreased significantly (p<0.005). The near point of accommodation also shifted inward signifi-cantly (p<0.05). There was no change in the far point of accommodation or empty field of accommodation, resulting in singnificant increase in the range of accommodation (p<0.01). The findings show that topical latanoprost treatment may induce physiological changes in the ciliary muscles in healthy human eyes.


Copyright © 2002, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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