糖尿病黄斑浮腫への硝子体手術の有効性

Efficacy of vitrectomy for diabetic macular edema

　糖尿病黄斑浮腫への硝子体手術の有効性を検討するために，両眼性の糖尿病黄斑浮腫の片眼に硝子体手術を実施し，他眼を対照群として硝子体手術前後の中心窩厚と視力を調べた。両眼に同様の黄斑浮腫があり，片眼術後5か月以上経過を追えた7例を対象とした。手術実施群の中心窩厚（平均）は，術前630μmが術後280μmに有意に減少した（p＜0.05）。対照群の中心窩厚（平均）は，術前590μmが490μmに減少したが有意差はなかった。手術実施群の術前後の視力は，改善3眼（43％）1不変3眼（43％），悪化1眼（14％）であった。同様に対照群では，視力の改善1眼（14％），不変2眼（29％），悪化4眼（57％）であった。糖尿病黄斑浮腫への硝子体手術の有効性が客観的に示された。

We assessed the efficacy of vitrectomy for diabetic macular edema by performing vitrectomy unilaterally in 7 patients. All the 7 patients had the same degree of diabetic macular edema in both eyes. They were followed up for 5 months or more. In operated eyes, the mean foveal thickness, or the distance between the inner foveal surface and the retinal pigment epithelium, decreased significantly from 630 μm to 280 μm (p＜ 0.05). In fellow eyes, it decreased from 590 μm to 490 μm with no significant difference. Postoperative visual acuity in 7 operated eyes improved by 2 lines or more in 3 eyes (43%), remained unchanged in 3 (43%), and decreased in 1 (14%). In the 7 fellow eyes, it improved in 1 eye (14%). remained unchanged in 2 (29%), and decreased in 4(57%) . These findings show that vitrectomy is effective for diabetic macular edema.