線維柱帯切除術直後の眼圧調整と長期予後

Early postoperative intraocular pressure and long-term outcome after trabeculectomy

（C4-1-11）　原発緑内障に対するマイトマイシンC併用線維柱帯切除術直後の眼圧調整が，長期予後に及ぼす影響について検討した。術後7日間，および術後8〜10日の3日間の2つの時期における平均眼圧8mmHg以上を高眼圧群，8mmHg未満を低眼圧群と分類し比較した。術後7日間における高眼圧群と低眼圧群のKaplan-Meier法による手術生存率に差はなかった。術後8〜10日における低眼圧群の手術生存率は，高眼圧群と比べ有意に高かった。術後合併症発生率はどちらの時期においても両群の間に差はなかった。マイトマイシンC併用線維柱帯切除術では術後9日前後の眼圧を十分に下降させることが手術成績を向上させると考えられた。

We reviewed 53 eyes which underwent trabeculectomy with topical mitomycin C. The series comprised primary open-angle glaucoma 42 eyes and primary angle-closure glaucoma 11 eyes. The postoperative intraocular pressure (TOP) was defined as high or low when the IOP was 8mmHg or more or under 8mmHg respectively. There was no difference in the surgical survival rate after Kaplan-Meier method between the high and low group during 7 days after surgery. The surgical survival rate was significantly higher in the low than the high group during the 8 to 10 days after surgery. There was no difference in the incidence of postoperative complications between the two groups in both periods. It appeared that sufficient lowering of IOP during the first 9 postoperative days will lead to long-term IOP control.