ぶどう膜炎による続発緑内障に対するマイトマイシンC併用線維柱帯切除術の成績

Outcome of trabeculectomy with adjunctive mitomycin C in uveitic glaucoma

　ぶどう膜炎による続発緑内障（UG）に対するマイトマイシンC併用線維柱帯切除術の成績について検討した。対象はUG 53例59眼で，Kaplan-Meier生命表を用い，原発開放隅角緑内障（POAG）65例82眼と比較検討した。UG群の術後21mmHg以下への最終眼圧調整率は術後5年で47.3％であり，POAG群と比べ有意に低下していたが，初回手術例のみで比較すると最終眼圧調整率は76.3％であり，有意差はなく良好であった。また術後の炎症再燃もわずかであった。マイトマイシンC併用線維柱帯切除術は，UGの初回手術には有用と考えられる。

We reviewed the outcome of trabeculectomy with adjunctive mitomycin C in uveitic glaucoma in 59 eyes of 53 patients. Another series of similarly treated 65 eyes with primary open-angle glaucoma (POAG) served as control. Eyes were defined as surgical success when the intraocular pressure was maintained at or below 21mmHg without oral medications 60 months after surgery. Using the Kaplan-Meier life-table method, the success rate was 47.3% in eyes with uveitic glaucoma and 90.3% in eyes with POAG. The series comprised 27 eyes of uveitic glaucoma and 61 eyes of POAG which were operated for the first time. The success rate was 76.3% in the former group and 90.3% in the latter. There was no significant difference between the two groups. Postoperatively, uveitis recurred in 2 eyes only in the uveitic group. The findings show that trabeculectomy withadjunctive mitomycin C is effective for uveitic glaucoma when performed as initial surgery.