Clinical features of acute conjunctivitis due to herpes simplex virus type 1 Satoshi Takeuchi 1 , Eiichi Uchio 1 , Norihiko Itoh 1 , Koki Aoki 2 , Shigeaki Ohno 1 1Dept of Ophthalmol, Yokohama City Univ Sch of Med 2Aoki Eye Clinic pp.281-284
Published Date 1999/3/15
DOI https://doi.org/10.11477/mf.1410906220
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We reviewed a series of 478 cases of corneal herpetic lesions or acute follicular conjunctivitis seen in an eye clinic in Hokkaido area during 12 years through 1994. Herpes simplex virus type 1 (HSV-1) was isolated in 23 cases (4.8%). The latter series comprised 3 children under 10 years of age (13%) and 15 adults aged 20 years or over (65%) . Only one eye was involved in 87% of the cases. It took an average of 8.3 days before clinical cure. It was difficult to differentiate cases due to HSV-1 from those of adenoviral conjunctivitis based on clinical features during the early stage of the disease. All cases were negative when examined by direct fluorescence antibody method, showing the possibility that biological difference may be present between strains obtained from the cornea and conjunctiva. The present findings illustrate that HSV may be involved in the etiology of acute conjunctivitis in adults.

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