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Two cases of adult T cell leukemia with cytomegalovirus retinitis as the initial manifestation Mariko Tsuji 1 , Yasuo Teshima 1 , Jun Sueda 1 , Ayako Ono 1 , Eiko Ikeda 1 , Kouichi Yoshimura 1 , Hiroshi Nagasaki 1 , Naofumi Hikita 1 , Manabu Mochizuki 1 , Ken Tanaka 2 , Kazunari Yamaguchi 3 1Dept of Ophthalmol, Kurume Univ Sch of Med 2Dept of Internal Med, Kurume Univ Sch of Med 3Blood Transfusion Service and Dept of Internal Med, Kumamoto Univ Sch of Med pp.546-550
Published Date 1998/4/15
DOI https://doi.org/10.11477/mf.1410905803
  • Abstract
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We diagnosed cytomegalovirus (CMV) retinitis in a 45-year-old male and a 76-year-old female.The first case was later diagnosed as chronic T-cell leukemia (ATL) . His CMV retinitis regressed after systemic ganciclovir. There has been no recurrence after treatment of ATL by chemotherapy.The second case was seropositive to human T cell lymphotropic virus type 1 (HTLV-I). She developed smoldering type of ATL 6 months later. Both cases showed decrease in the number of CD8+ lymphocytes. The number of CD4+ lymphocytes was normal when CMV retinitis was diagnosed. There cases seemed to suggest that CD8+ lymphocytes is involved in the development of CMV retinitis.


Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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