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Cytomegalovirus retinitis in adult T-cell leukemia Yasuhiro Kishikawa 1 , Hiroko Deguchi 1 , Kazuaki Mishima 1 , Takashi Kitaoka 1 , Tsugio Amemiya 1 , Hiroyuki Mori 2 , Masao Tomonaga 2 1Dept of Ophthalmol, Nagasaki Univ Sch of Med 2Atomic Disease Institute, Dept of Hematol, Nagasaki Univ Sch of Med pp.1411-1415
Published Date 2001/7/15
DOI https://doi.org/10.11477/mf.1410907440
  • Abstract
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A 63-year-old man noted blurring of vision in both eyes. He had been under treatment for adult T- cell leukemia and pneumonia by pneumocystis carinii and cytomegalovirus (CMV) . His left eye showed inflammatory cells in the anterior chamber. Both eyes showed exudates and tomato ketchup-like hemorrhages in the fundus. These findings led to the diagnosis of CMV retinitis. Intravenous ganciclovir induced decreased level of CMV antigen and improved fundus findings. The CMV antigen level increased again followed by exacerba-tion of fundus findings. Substitution of ganciclovir by foscarnet failed to show lasting improvement. It appeared that CMV resistant to multiple drugs was involved in this patient.


Copyright © 2001, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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