Human papilloma virus in the conjunctiva in ocular surface diseases Wakako Adachi 1 , Kohji Nishida 1 , Akiyo Shimizu 1 , Hisano Soma 2 , Norihiko Yokoi 1 , Shigeru Kinoshita 1 1Dept of Ophthalmol, Kyoto Prefectural Univ of Med 2Dept of Ophthalmol, Uji Tokushukai Hosp pp.439-442
Published Date 1995/3/15
DOI https://doi.org/10.11477/mf.1410904210
  • Abstract
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We tried to identify human papilloma virus (HPV) in ocular surface diseases characterized by abnormal epithelial proliferation. We used polymerase chain reaction to detect HPV type 16 and type 18 DNA in idiopathic ocular surface disorder 3 eyes, conjunctival tumor 2 eyes and 9 normal eyes. HPV type 16 DNA was detected in 1 case of conjunctival squamous cell carcinoma and in no other eyes. HPV type 18 DNA was consistently absent. The findings imply that HPV type 16 is associated with the pathogenesis of conjunctival squamous cell carcinoma.

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