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Involvement of vitamin B12 in optic nerve disorders Hidehiro Oku 1 , Jun Sugasawa 1 , Takashi Utsumi 1 1Dept of Ophthalmol, Osaka Med Coll pp.1617-1620
Published Date 1994/9/15
DOI https://doi.org/10.11477/mf.1410903984
  • Abstract
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We quantitated the level of vitamin B12 and its unsaturated binding capacity in the serum and cerebrospinal fluid in 14 cases of optic nerve disorders. The series comprised idiopathic optic neuritis 8 cases, ischemic optic neuropathy 3, toxicity from inhalation of organic solvent 2 and Leber's hereditary optic atrophy 1. Significant reduction of B12 in the cerebrospinal fluid under 10pg/ml was present in 6 cases of optic neuritis, 75%. No such finding was observed in cases of ischemic optic neuropathy. These differences seemed to reflect the various causes and clinical features of optic nerve disorders.


Copyright © 1994, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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