Treatment of Behçet disease with systemic cyclosporin and colchicine Mariko Kitazawa 1 , Jiro Numaga 1 , Yujiro Fujino 2 , Kiyofumi Hayashi 2 , Yasuho Izawa 2 , Kanjiro Masuda 2 1Dept of Ophthalmol, Branch Hosp, Sch of Med, Univ of Tokyo 2Dept of Ophthalmol, Sch of Med, Univ of Tokyo pp.1401-1404
Published Date 1994/7/15
DOI https://doi.org/10.11477/mf.1410903945
  • Abstract
  • Look Inside

We evaluated the effect of concurrent use of systemic cyclosporin and colchicine on 58 eyes of32 cases of Behçet disease. All the patients had been treated by systemic cyclosporin before. The ages ofpatients ranged from 23 to 57 years, average 38.4 years. The current treatment was continued for 2 to 70months, average 29 months. The frequency of ocular attacks decreased significantly from 4.4 to 2.2 times peryear. Adverse side effects included impaired renal function 34%, diarrhea 31%, impaired liver function 28%,systemic hypertension 13% among others. These side effects disappeared after decrease or withdrawal ofcolchicine.

Copyright © 1994, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院